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 Paranasal Sinus and Nasal Cavity Cancer Risk Factors

  • Age over 40
  • Male
  • SmokingChronic sinusitis
  • Nasal polyps (particularly in cases of inverted papilloma)
  • HPV (human papillomavirus) infection (inverted papilloma)
  • EBV infection (in cases of T cell lymphoma)
  • Asian or South American ancestry (T cell lymphoma)
  • Certain autoimmune diseases (B cell lymphoma)
  • Neurofibromatosis (in sarcomas)
  • Occupational exposure to certain chemicals or dust – such jobs include:
    • Furniture manufacturing
    • Sawmill work
    • Woodworking (carpentry)
    • Shoemaking
    • Leather tanning
    • Metal plating
    • Flour mill or bakery work
    • Welding/soldering

            Suspect substances include:

    • Nickel compounds
    • Chromium compounds
    • Lacquers
    • Mineral oils
    • Wood dust

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