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 Specialized training in the emerging discipline of cancer genetics requires a highly focused interdisciplinary and collaborative approach in order to capitalize on rapid advances in basic scientific knowledge and to maximize the potential benefits to science and society. The diverse experience of the investigators and the multidisciplinary infrastructure of City of Hope’s Division of Clinical Cancer Genetics, combined with its collaboration with leading City of Hope/Beckman Research Institute and University of Southern California researchers and educational programs, give the Cancer Genetics Career Development Program the robust resources required to produce world class investigators and mission-critical allied health professionals who will contribute significantly to the growing body of cancer genetics research.
The CGCDP draws upon the knowledge and experiences of a diverse faculty and consultants who are nationally recognized experts in their fields. A partial listing of City of Hope mentors, faculty members and extramural consultants represents the multiple disciplines germane to comprehensive cross-disciplinary training in cancer genetics research. Mentors were chosen from among City of Hope and USC faculty to represent a broad spectrum of relevant basic science and clinical research disciplines. Additional researchers with investigational focus related to chosen research projects are also accessible to allow Trainees to tailor their mentorship specifically to their project design and research goals. Because of the interdisciplinary nature of the proposed training, each Trainee will have at least two mentors with expertise in different disciplines.
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Jeffrey N. Weitzel, M.D.
Chief, Division of Clinical Cancer Genetics
Professor of Oncology Population Sciences
Director, Cancer Screening & Prevention Program Network
Director, Cancer Genetics Education Program | Clinical cancer genetics, health services research, molecular oncology, disparities and Latino health, targeted therapy for hereditary cancer and clinical prevention. | Kathleen Blazer, M.S., C.G.C., Ed.D. Cancer Risk Counselor; Assistant Director, Cancer Genetics Education Program, Division of Clinical Cancer Genetics | Clinical cancer genetics, genetic counseling, education, bioethics | Deborah J. MacDonald, Ph.D., M.S., A.P.N.G. Cancer Risk Counselor; Assistant Professor, Division of Clinical Cancer Genetics
| Clinical cancer genetics, nursing, cancer communications | Kimlin Ashing-Giwa, Ph.D. Director, Center of Community Alliance for Research and Education (CCARE)
| Community participatory research, Behavioral Science, minority and disparities research | William Bennett, M.D. Associate Professor, Division of Thoracic Surgery
| Molecular epidemiology and environmental carcinogenesis | Leslie Bernstein, Ph.D. Professor and Director, Division of Cancer Etiology Dean for Faculty Affairs
| | Ravi Bhatia, M.D. Director, Division of Hematopoietic Stem Cell and Leukemia Research Co-leader, Hematologic Malignancies Program, Comprehensive Cancer Center Professor, Hematology & Hematopoietic Cell Transplantation
| Regulation of normal and malignant hematopoietic stem and progenitor cells, therapeutic targeting of malignant stem cells, and hematopoietic stem cell therapeutics | Smita Bhatia, M.D., M.P.H. Chair and Professor, Department of Population Sciences Associate Director for Population Research and Co-leader, Cancer Control and Population Sciences Program, Comprehensive Cancer Center Director, Center for Cancer Survivorship Director, Outcomes Research Staff Physician, Pediatrics
| Cancer epidemiology, Quality of Life research/survivorship; issues related to long-term complications among survivors | Shiuan Chen, Ph.D. Director, Division of Tumor Cell Biology Professor and Associate Chair, Department of Cancer Biology Co-director, Breast Cancer Program
| Hormonal breast cancer biology, aromatase, natural compounds | Betty Ferrell, Ph.D., F.A.A.N. Professor, Division of Nursing Research
| Nursing research, qualitative methods, ovarian cancer quality of life, survivorship | Stephen J. Forman, M.D., F.A.C.P. Chair, Department of Hematology & Hematopoietic Cell Transplantation Francis and Kathleen McNamara Distinguished Chair in Hematology and Hematopoietic Cell Transplantation Co-leader, Hematologic Malignancies Program, Comprehensive Cancer Center Clinical Director, Department of Cancer Immunotherapeutics & Tumor Immunology Professor, Department of Medical Oncology & Therapeutics Research Visiting Associate, Chemical Engineering, California Institute of Technology
| Hematology, bone marrow transplantation, stem cell therapy, breast cancer | Marcia Grant, D.N.Sc., F.A.A.N. Director and Professor, Division of Nursing Research
| Qualitative and quantitative outcomes in cancer care, nursing research, education, Quality of Life | Richard Jove, Ph.D. Director, Beckman Research Institute Deputy Director, Comprehensive Cancer Center Morgan and Helen Chu Director’s Chair, Beckman Research Institute Professor, Department of Molecular Medicine
| Regulatory mechanisms of STAT signal transduction pathways and the roles in oncogenesis | Theodore Krontiris, M.D, Ph.D. Director Emeritus, Comprehensive Cancer Center Professor, Department of Molecular Medicine
| Genetic risk and disease, unstable repetitive genetic elements, multiplex modifier gene interactions | Garrett Larson, Ph.D. Director, Genetic Markers Core Associate Research Professor, Department of Molecular Medicine
| Molecular genetics, cancer sib-pair studies, SNP and haplotype analyses | Lucille Leong, M.D. Professor, Department of Medical Oncology & Therapeutics Research
| Medical oncology, experimental therapeutics, clinical trials, graduate education | Marcia M. Miller, Ph.D. Director, Electron Microscopy Core Facility Professor, Department of Molecular and Cellular Biology
| | Susan L. Neuhausen, Ph.D. Morris & Horowitz Families Professor in Cancer Etiology and Outcomes Research Professor, Department of Population Sciences
| Molecular genetics, hereditary breast and ovary cancer genetics, BRCA gene modifiers | Joyce Niland, Ph.D. Chair and Professor, Department of Information Sciences Edward and Estelle Alexander Chair in Information Sciences Associate Director for Information Sciences, Comprehensive Cancer Center Director and Professor, Division of Clinical Research Information Management
| Biostatistics, biomedical informatics and clinical trials | Timothy O’Connor, Ph.D. Professor, Division of Biology
| DNA Repair and genomic stability in cancer | Gerd Pfeifer, Ph.D. Professor and Chair, Department of Cancer Biology Lester M. and Irene C. Finkelstein Chair in Biology Co-leader, Cancer Biology Program, Comprehensive Cancer Center
| epigenetics and mutagenesis | John J. Rossi, Ph.D. Lidow Family Research Chair Dean, City of Hope's Irell & Manella Graduate School of Biological Sciences Chair and Professor, Department of Molecular and Cellular Biology Associate Director for Laboratory Research and Co-leader, Cancer Biology Program, Comprehensive Cancer Center
| RNA biology, cancer and gene therapy, ribozymes, Si-RNA | Binghui Shen, Ph.D. Director, Division of Radiation Biology Professor and Associate Chair, Department of Cancer Biology
| Biology of structure-specific nucleases, susceptibility to cancer, and genomic stability | John Shively, Ph.D. Chair and Professor, Department of Immunology Associate Dean, City of Hope's Irell & Manella Graduate School of Biological Sciences
| CEACAM genes, breast cancer proteomics, prostate cancer | Andrea Thornton, Ph.D. Chief, Division of Psychology Assistant Professor and Psychologist, Department of Supportive Care Medicine Assistant Professor of Behavioral Oncology, Department of Population Sciences
| Molecular pharmacology and experimental therapeutic research | Yun Yen, M.D., Ph.D. Associate Director for Translational Research, Comprehensive Cancer Center Dr. & Mrs. Allen Y. Chao Chair in Developmental Cancer Therapeutics, Endowed Chair Co-leader, Developmental Cancer Therapeutics Program, Comprehensive Cancer Center Professor and Chair, Molecular Pharmacology Professor, Medical Oncology & Therapeutics Research
| Molecular pharmacology and experimental therapeutic research | Victoria Cortessis, Ph.D. Assistant Professor, Department of Preventive Medicine, University of Southern California
| Epidemiology and of breast cancer and hormones; SERMS and AI |
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Harry Burke, M.D., Ph.D. Associate Program Director and Director of Research, Department of Medicine, George Washington University School of Medicine
| Advanced statistical modeling of gene microarrays and protein spectra, predominately in cancer | Rowan Chlebowski, M.D. Principle Investigator, Women’s Health Initiative site Professor of Medicine and Chief, Division of Medical Oncology and Hematology, Harbor-UCLA Medical Center
| Epidemiology and of breast cancer and hormones; SERMS and AI | Victoria Cortessis, Ph.D. Assistant Professor, Department of Preventive Medicine, University of Southern California
| Epidemiology of familial testicular cancer | Fergus J. Couch, Ph.D. Mayo Clinic
| Molecular genetics, HBOC genetics, BRCA gene modifiers | Roberta McKean-Cowdin Assistant Professor, Norris Comprehensive Cancer Center, University of Southern California
| Brain cancers and tumors in children; breast cancer; variant genes | Steven Narod, M.D. Chair, Breast Cancer Research, Centre for Research in Women's Health, University of Toronto
| Hormonal determinants and modifiers of cancer risk in BRCA carriers, familial risk modeling | Malcolm Pike, Ph.D. Thornton Chair and Professor, Preventive Medicine, University of Southern California
| Cancer epidemiology, hormonal chemoprevention |
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