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 Selected Publications

Lundberg, P., Chandran R., Brown, J., Tyszka, M.J., Hamamura, M., Hinton, D.R., Kovats, S., Nalcioglu, O., Weinberg, K., Openshaw, H., and Cantin, E.M. The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice is a Major Cause of CNS Pathology Resulting in Fatal Encephalitis. Journal of Virology, (In Press), 2008

Lundberg, P., Welander PV, Edwards, CK 3rd, Van Rooijen, Cantin E.M.  Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2. J. Virol. 81(3): 1451-60, 2007

Amarzguioui, M., Lundberg, P., Cantin E.M., Hagstrom, J., Behlke, M., and Rossi, J.J.  Rational design and in vitro/in vivo delivery of Dicer substrate siRNAs. Nature Protocols 1(2): 508-51, 2006

Guest Editor:  Cantin, E.M. Immunology of Herpesvirus Infection. Viral Immunol.18 (3): 408-10
Special focus issue of Viral Immunology, 2005

Openshaw H., Cantin E.M.  Editorial commentary, Corticosteroids in herpes simplex encephalitis. J. Neurol. Neurosurg. Psychiatry 76(11): 1469-7, 2005

Kim, DH., Longo, M., Han, Y., Lundberg, P., Cantin, E.M., and Rossi, J.J.  Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.  Nature Biotechnology, 22 (3): 321-5, 2004

Lundberg, P., Han, X., Welander, P., and Cantin, E.M. Herpes Simplex Virus type 1 (HSV-1) DNA is Immunostimulatory In vitro and in vivo; A Potential role in Pathogenesis?   Journal of Virology 77 (20): 11158-69, 2003.

Lundberg, P., and Cantin, E.M.  A Potential role for CXCR3 Chemokines in the response to ocular HSV infection. Current Eye Research 26 (3-4): 137-150, 2003.

Lundberg, P., Welander, P., Openshaw, H., Edwards, C.K., Nalbandian, C., Moldowar, L., and Cantin, E.M. A Locus on Mouse Chromosome 6 that Determines Resistance to Herpes Simplex Virus also Influences Reactivation, While an Unlinked Locus Augments Resistance of Female Mice.  Journal of Virology, 77 (21): 11661-73, 2003.

Han, X., Lundberg, P., Tanamachi, B., Openshaw, H., Longmate, J., Cantin, E.M.  Gender influences HSV-1 infection in normal and interferon-gamma mutant mice. [Erratum appears in J Virol 2001 Aug; 75(16): 7789]. Journal of Virology. 75(6): 3048-3052, 2001.

Cantin, E.M., Tanamachi, B., Mann, J., Openshaw, H., and Clarke, K.  Interferon gamma receptor mutant mice are more susceptible to herpes simplex virus type 1 infection than interferon gamma ligand null-mutant mice.  Journal of Virology.  73 (6): 5196-200, 1999.

Cantin, E.M., Mann, J. Genetic Variation Among 129 Substrains Practical Consequences Correspondence. Journal of Immunol. 162(10):6294, 1999.

Cantin, E.M., Tanamachi, B., Openshaw, H.  Role for gamma interferon in control of herpes simplex virus type-1 reactivation.  Journal of Virology 73 (4): 3418-3423, 1999.

Eberle, R., Cantin, E.M., Openshaw, H., Tanamachi, B.  Genetic and functional complementation of the HSV1 UL27 gene and gB glycoprotein by simian alpha-herpesvirus homologs.   Arch. Virol. 142:721 736, 1997.

Lin, X.H., Ali, M.R., Openshaw, H., Cantin, E.M.  Deletion of the carboxy terminus of herpes simplex virus type I (HSV 1) glycoprotein B does not affect oligomerization, heparin binding activity, or its ability to protect against HSV challenge.  Arch. Virology 141(6): 1153 1156, 1996

Ali, M.R., Forghani, B., Cantin, E.M.  Characterization of an essential HSV 1 protein encoded by the UL25 gene reported to be involved in virus penetration and capsid assembly.  Virology 216 (1): 278 283, 1996.

Cantin, E.M., Hinton, D.R., Chen, J., Openshaw, H.  Gamma Interferon Expression during acute and latent nervous system infection by herpes simplex virus type 1.  Journal of Virology 69(8): 4898 4905, 1995.

Openshaw, H., McNeill, J.I., Lin, X.H., Niland, J. and Cantin, E.M.  Herpes Simplex Virus DNA in normal corneas:  Persistence without viral shedding from ganglia.  Journal of Medical Virology 46:75 80, 1995.

Cantin, E.M., Chen, J., Gaidulis, L., Valo, Z., McLaughlin Taylor, E.  Detection of Herpes Simplex Virus DNA Sequences in Human Blood and Bone Marrow Cells.  Journal of Medical Virology 42:279 286, 1994.

Cantin, E.M., and Woolf, T.  Antisense Oligonucleotides:  Prospects and Problems.  Trends in Microbiology 1:249 283, 1993  (Invited Review).

Lange, W., Cantin, E.M., Finke, J., Dolken, G.  In Vitro and In Vitro Effects of Synthetic Ribozymes Targeted against BCR/ABL mRNA.  Leukemia 7:1786 1794, 1993.

Cantin, E.M., Podsakoff, G., Willey, D.E., Openshaw, H.  Antiviral effects of herpes simplex virus specific anti sense nucleic acids.  Advances in Experimental Medicine and Biology 312:139 49, 1992.

Cantin, E.M., Chen, J., Willey, D., Taylor, J.L., O'Brien, W.J.  Persistence of Herpes Simplex Virus DNA in Rabbit Corneal Cells.  Invest Ophthal Vis Sci 33:2470 2475, 1992.

Cantin, E.M., Chen, J., McNeill, J., Willey, D.E., Openshaw, H.  Detection of herpes simplex virus DNA sequences in corneal transplant recipients by polymerase chain reaction assays.  Current Eye Research 10:15 21, 1991.

Cantin, E.M., Lange, W. and Openshaw, H.  Application of Polymerase Chain Reaction Assays to Studies of Herpes Simplex Virus Latency.  Intervirology 32:93 100, 1991.

Cantin, E.M., Podsakoff, G., Willey D.E., Openshaw, H.  Antiviral effects of herpes simplex virus specific anti sense nucleic acids.  In:  Innovations in Antiviral Development and the Detection of Virus Infections.  Edited by L.R. Walsh.  Plenum Press, New York. Pages 139-149, 1991.

Zaia, J.A., Cantin, E.M., Chang, P.S., Sarver, N., and Rossi, J.J.  Antiviral Evaluation of HIV 1 Specific Ribozyme Expressed in CD4 + HeLa Cells.  In Advances in Molecular Biology and Targeted Treatments for AIDS.  Plenum Publishing Corp, New York.  Pages 335 343, 1991.

Chang, P.S., Cantin, E.M., Zaia, J.A., Ladne, P.A., Stephens, D.A., Sarver, N. and Rossi, J.J.  Ribozyme mediated site-specific cleavage of the HIV 1 genome.  Clinical Biotechnology 2:1 8, 1990.

Rossi, J.J., Cantin, E.M., Zaia, J.A., Ladne, P.L., Chen, J., Stephens, D.A., Sarver, N. and Chang, P.S.  Ribozymes as therapies for AIDS.  Annals of New York Academy of Science, 1990.

Sarver, N., Cantin, E.M., Chang, P.S., Ladne, P., Stephens, D., Zaia, J.A. and Rossi, J.J.  Ribozymes as potential HIV 1 therapeutic agents.  Science, 247:1222 1225, 1990.

Openshaw, H., Cantin, E.M. and Hinton, D.  Potential interactions of HIV and the neurotropic herpesviruses in AIDS encephalopathy.  In: Herpesvirus, the Immune System, and AIDS.  Developments in Medical Virology.  Y. Becker, and L. Aurelian, Editors.  Kluwer Academic Publishers, Norwell, MA.   Chapter 10, Pp. 227 248, 1990.

Sarver, N., Hampel, A., Cantin, E.M., Chang, P., Tritz, R., Zaia, J.A. and Rossi J.J.  Exploring catalytic RNAs as potential HIV 1 therapeutic agents, In: Gene regulation, oncogenesis and AIDS. Takis S. Papas, Editor, Portofolio Publishing Co., Texas, 1990.

Sarver, N., Cantin, E.M., Chang, P.S., Ladne, P.A., Stephens, D.A., Zaia, J.A. and Rossi, J.J.  Ribozymes as potential HIV 1 therapeutic agents.  Science 247:1222 1225, 1990.

Rossi, J.J., Cantin, E.M., Sarver, N., Chang, P.F.  The potential use of catalytic RNAs in therapy of HIV infection and other diseases.  Pharmacology and Therapeutics 50 (2): 245 54, 1990.

Rossi, J.J., Cantin, E.M., Zaia, J.A., Ladne, P.L., Chen, J., Stephens, D.A., Sarver, N. and Chang, P.S.  Ribozymes as therapies for AIDS.  Annals of New York Academy of Science, 1990.

Sarver, N., Cantin, E.M., Chang, P.S., Ladne, P., Stephens, D., Zaia, J.A. and Rossi, J.J.  Ribozymes as potential HIV 1 therapeutic agents.  Science, 247:1222 1225, 1990.

Openshaw, H., Cantin, E.M. and Hinton, D.  Potential interactions of HIV and the neurotropic herpesviruses in AIDS encephalopathy.  In: Herpesvirus, the Immune System, and AIDS.  Developments in Medical Virology.  Y. Becker, and L. Aurelian, Editors.  Kluwer Academic Publishers, Norwell, MA.   Chapter 10, Pp. 227 248, 1990.

Sarver, N., Hampel, A., Cantin, E.M., Chang, P., Tritz, R., Zaia, J.A. and Rossi J.J.  Exploring catalytic RNAs as potential HIV 1 therapeutic agents, In: Gene regulation, oncogenesis and AIDS. Takis S. Papas, Editor, Portofolio Publishing Co., Texas, 1990.

Sarver, N., Cantin, E.M., Chang, P.S., Ladne, P.A., Stephens, D.A., Zaia, J.A. and Rossi, J.J. Ribozymes as potential HIV 1 therapeutic agents.  Science 247:1222 1225, 1990.

Rossi, J.J., Cantin, E.M., Sarver, N., Chang, P.F.  The potential use of catalytic RNAs in therapy of HIV infection and other diseases.  Pharmacology and Therapeutics 50 (2): 245 54, 1990

Martin, S., Cantin, E.M. and Rouse, B.T.  Evaluation of antiviral immunity using vaccinia virus recombinants expressing cloned genes for herpes simplex virus type 1 glycoproteins. J. Gen. Virol. 70:1359 1370, 1989.

Eskinazi, D.P. and Cantin, E.M.  Some monoclonal antibodies to HSV infection related antigens cross react with some tumor cell lines and tumor tissue sections, Oral Surg., Oral Med., and Oral Pathol. 65:308 315, 1988.

Martin, S., Cantin, E.M., and Rouse, B.T.  Cytotoxic T lymphocytes: their relevance in herpesvirus infections.  Ann. New York Acad. Sci. 532:257 272, 1988.

Cantin E.M., Eberle, R., Baldick, J.L., Moss, B., Willy, D.E., Notkins, A.L., and Openshaw, H. Expression of herpes simplex virus 1 glycoprotiens B by a recombinant vaccinia virus and protection of mice against lethal herpes simplex virus 1 infection. Proc Natl Acad Sci USA 84:5908-5912, 1987

Puga, A., Gomez Marquez, J., Brayton, P.R., Cantin, E.M., Long, L.K., Baracid, M, and Notkins, A.L. The immediate early enhancement of herpes simplex virus type 1 can replace a regulatory region of C Ha vas 1 oncogene required for transformation.  J. Virol. 54:879 881, 1985.

Sekizawa, T., Openshaw, H., Cantin, E.M., Puga, A., Notkins, A.L. Herpes simplex virus. Clin. Virol. (Japan) 12:419 424, 1985.

Puga, A., Cantin, E.M., Wohlenberg, C., Openshaw, H. and Notkins, A.L.  Different sizes of restriction endonuclease fragments from the terminal repetitions of the herpes simplex virus type 1 genome latent in trigeminal ganglia of mice.  J. Gen. Virol. 65:437 444, 1984.

Cantin, E.M. and Puga, A. and Notkins, A.L.:  Molecular biology of herpes simplex virus latency.  In: Concepts in Viral Pathogenesis.  Editors: Notkins, A.L. and Oldstone, M.B.A., Pp. 172 177, Springer Verlag, New York, 1984.

Puga, A. Cantin, E.M., and Notkins, A.L.  Homology between murine and human cellular DNA sequences and the terminal repetition of the S component of the herpes simplex virus type 1 genome.  Cell 31:81 87, 1982.

Openshaw, H., Sekizawa, T., Cantin, E.M., Puga, A. and Notkins, A.L.   Latency and reactivation of herpes simplex virus:  Animal models.  In: Viral Infections in Oral Medicine.  J. Hooks and G. Jordan, Editors.  Elsevier/North Holland.  Pages 79 88, 1981.


This is a partial list. Full publications list avaiable upon request. Information on this page may be self-reported and subject to change at any time. Last updated 08/08.

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